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Invitrogen
MBL2 Monoclonal Antibody (11C9)
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MBL2 Antibody (HYB 131-11-02) in WB
Molecular medicine reports 2012 -
Figure 4 MBL proteins were submitted to SDS-PAGE and western blotting using anti-MBL mAb HYB 131-11 as the primary detecting antibody. (A) Recombinant wild-type MBL was analyzed under non-reducing (lanes 1 and 3) and reducing conditions (lanes 2 and 4). (B) Three variant MBL proteins were analyzed under non-reducing conditions. Lanes 1 and 4, 32Cys MBL; lanes 2 and 5, 34Asp MBL and lanes 3 and 6, 37Glu MBL.... View More
产品信息
HYB 131-11-02
应用
建议稀释比
已发表文章
产品规格
已发表种属
Non-human primate
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
11C9
抗原
Human MBL.
偶联物
形式
Liquid
浓度
1.1 mg/mL
保存条件
4°C
运输条件
Wet ice
RRID
产品详细信息
HYB 131-11-02 is specific for MBL from human serum or plasma.
HYB 131-11-02 has been successfully used in ELISA and Western blotting procedures. HYB 131-11-02 reacts with human MBL both in its polymeric state and as a single subunit of molecular mass 26 kDa.
The HYB 131-11-02 immunogen is human MBL.
Epitope specificity differs from that of HYB 131-01-02 and HYB 131-10-02.
NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL
靶标信息
MBL2 is a calcium-dependent lectin involved in innate immune defense. It binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. It also binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. MBL2 may bind DNA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
